Quantitative Prediction of Human Pharmacokinetics and Pharmacodynamics of CKD519, a Potent Inhibitor of Cholesteryl Ester Transfer Protein (CETP)

CKD519, a selective inhibitor of cholesteryl ester transfer protein(CETP), is undergoing development as an oral agent for the treatment of primary hypercholesterolemia Lids and mixed hyperlipidemia.The aim of this study was to predict the appropriate efficacious dose of CKD519 for humans in terms of the inhibition of CETP activity by developing a C

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Contextualizing Western guidelines for stroke and low back pain to a developing country (Philippines): an innovative approach to putting evidence into practice efficiently

Consuelo Gonzalez-Suarez,1,2,3 Karen Grimmer-Somers,1 Janine Margarita Dizon,1 Ellena King,1 Sylvan Lorenzo,2 Carolina Valdecanas,2 Ephraim Gambito,2 Belinda Fidel2,31International Center for Allied Health Evidence, University of South Australia, Adelaide, Australia; 2Philippine Academy of Rehabilitation Medicine, Quezon City, Philippines; 3Univers

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